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Rab11a function

WebOct 31, 2024 · From these observations, we suggest a novel function of Rab11A as a negative regulator of osteoclastogenesis mainly through (i) abolishing the surface … WebSrc-family kinase signaling, actin-mediated membrane trafficking and organellar dynamics in the control of cell fate: Lessons to be learned from the adenovirus E4orf4 death factor

A role for Rab11 in the homeostasis of the endosome-lysosomal ... - Pu…

WebRab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the recycling of … WebHere we show, using conditional gene ablation and three-dimensional tissue culture, that the homeobox transcription factor Cdx2 controls apical–basolateral polarity in mouse enterocytes and human colonic epithelial cells. Cdx2 regulates a comprehensive gene network involved in endo-lysosomal maturation and protein transport. ear and arm pain https://cfcaar.org

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WebExpression of wild-type Rab11a in Rab11a knockout cells rescued the late endosome/lysosome phenotype. Overall, these results indicate that Rab11a and Rab11b … WebThe Kunitz-type recombinant protein, Amblyomin-X, is an antitumor recombinant molecule from a cDNA library prepared from the salivary glands of the ti… Web16 hours ago · Epithelial tissues are the most common, widely distributed, and perform several particular functions. ... In particular, Rab11a[S25N] is a GDP-locked form, … ear and allergy associates

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Rab11a function

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WebMar 1, 2024 · Study question: Is Rab11a GTPase, a regulator of intracellular trafficking, of significance in endometrial functions? Summary answer: Rab11a is an important … WebNov 18, 2024 · The Rab GTPase Rab11 has been shown to be essential to epithelial lumen formation in vitro, however few studies have addressed its functions in vivo and none …

Rab11a function

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WebReviewed Preprint posted 14 April 2024 Posted to bioRxiv 16 February 2024Go to bioRxiv Sent for peer review 15 February 2024 WebMicrovillus inclusion disease (MVID) is a constitutive intestinal epithelial disease which causes definitive intestinal failure and cholestatic liver disease primarily caused by mutations in the Myosin Vb gene. Genotype-clinical phenotype associations suggest that the progression of liver disease can be predicted through a correlation between myosin Vb …

WebRab11 has 3 isoforms, Rab11a, Rab11b and Rab11c with Rab11a and Rab11b having 89% amino acid similarity, indicating that the two isoforms could serve some redundant … WebDec 31, 2024 · Our data did not reveal a significant change in endometrial Rab11a expression from pre-receptive to receptive phase. Nonetheless, considering that …

WebRAB11A Protein Overview. Using PCR to amplify Ras and Ras-like sequences from carcinoma and T-cell cDNA libraries, Drivas et al. (1991) obtained a cDNA encoding … WebOct 31, 2024 · Rab11A and Rab11B in osteoclasts have a similar function that negatively regulates osteoclastogenesis through proteolytic control of the cell surface receptors, …

WebP62491 - RAB11A - Ras-related protein Rab-11A - Function. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles …

WebRAB11A. YL8. RAB11A, member RAS oncogene family. GO Process (24) GO Function (7) GO Component (12) Gene Ontology Biological Process. GTP catabolic process [IBA, IDA] ... earandbWebThe present study reveals the complexity of the trafficking of pIgR to the apical plasma membrane in epithelial cells with exocrine secretory functions; in rabbit lacrimal gland acinar cells (LGACs), trafficking of pIgR involves both the transcytotic pathway and one arm of the regulated secretory pathway. csr water chalkWebRab11a and Rab8a are ubiquitous small GTPases shown as required for rhodopsin transport in Xenopus laevis and zebrafish photoreceptors by dominant negative (dn) disruption of function. Here, we generated retina-specific Rab11a (retRab11a) and Rab8a (retRab8a) single and double knockout mice to explo... csr water neckWebNX_P62491 - RAB11A - Ras-related protein Rab-11A - Function. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport … ear and back of head painWebNov 27, 2024 · Protein aggregation and accumulation are common pathological hallmarks in neurodegenerative diseases. To efficiently clear and eliminate such aggregation becomes an important cellular strategy for cell survival. Lewy bodies inclusion and aggregation of α-Synuclein (α-Syn) during the pathogenesis of Parkinson’s disease (PD) serve as a good … csr water neck fittingsWebExamination of Rab11a function in enteroids or cultured cell lines suggested that this endosome unit is required for suppression of the Yap pathway by Hippo kinases. ear and back blackheadsWebCo-ordination of Rab GTPase function has emerged as a crucial mechanism in the control of intracellular trafficking processes in eukaryotic cells. Here, we show that GRAB/Rab3IL1 [guanine nucleotide exchange factor for Rab3A; RAB3A interacting protein (rabin3)-like 1], a protein that has previously be shown to act as a GEF (guanine nucleotide exchange … csr weatherboards